I-Keto ne-Gout: Ingabe Ukudla Kwe-Keto Kungasiza Izimpawu Ze-Gout?

Uma udla inyama, inhlanzi, noma inyama yesitho, ungase uzibuze: ingabe lokhu kudla kwe-keto-friendly kwandisa ingozi yokuthuthukisa i-gout?

Phela, ukuhlakanipha okuvamile kubamba ukuthi ukudla okuphezulu kwamaprotheni kanye nokudla okunamafutha aphezulu kuyimbangela yokuhlaselwa yi-gout.

Nakuba kunengqondo ngale mbono, luncane kakhulu ucwaningo olusekela ukuxhumana phakathi kwamaprotheni ezilwane, ukudla okunempilo okunamafutha aphezulu, kanye nobungozi be-gout.

Nokho, kunezinye izimbangela ze-gout, futhi ukudla ukudla okuseqophelweni eliphezulu kungenye yezindlela ezingcono kakhulu zokuvimbela noma ukukhulula i-gout.

Iyini i-gout?

I-Gout iwuhlobo lwesifo samathambo esibangelwa ukunqwabelana okubuhlungu kwamakristalu e-uric acid emalunga, imisipha, namachopho, ikakhulukazi amalunga ezandla nezinzwane ezinkulu.

Amakristalu e-uric acid akha lapho amazinga egazi e-uric acid efika emazingeni aphezulu ngokungavamile. Lesi simo sibizwa nge-hyperuricemia, futhi siwuphawu oluyinhloko lwengozi ye-gout.

Kodwa-ke, kubalulekile ukuqaphela ukuthi i-gout ayitholakali kalula: kuphela u-5% wabantu abane-uric acid engaphezu kuka-9 mg/dL (okubhekwa njenge-hyperuricemia) ababa ne-gout.

Emakhulwini eminyaka adlule, i-gout yaziwa ngokuthi "isifo samakhosi" futhi "isifo somuntu ocebile." Kuvele ukuthi abantu abacebile yibona kuphela abantu ababekwazi ukuthenga ushukela, manje osekubhalwe phansi ukuthi ubungozi be-gout.

I-Gout ithinta cishe i-1-4% yabantu (3-6% yamadoda kanye ne-1-2% yabesifazane). Emhlabeni wonke, ukwanda kwe-gout kuye kwanda, ngokunokwenzeka ngenxa yemikhuba yokudla ewohlokayo, ukungawuvivinyi umzimba, nokwenyuka kwamazinga okukhuluphala kanye nesifo se-metabolic. Kubonakala futhi kunengxenye yofuzo engozini ye-gout ( ¹ ).

Ukuze welaphe i-gout, odokotela bavame ukunikeza imithi eyenza i-uric acid ikhiqizwe, noma basikisele ukudla okune-protein ephansi. Kodwa ucwaningo olusha lunikeza ukukhanya ngezimbangela ze-gout, futhi kuyacaca ukuthi kunezindlela ezingcono kunokusika amaprotheni ukuze kukhishwe i-gout.

Ibangelwa yini i-gout?

I-Gout yenzeka lapho amakristalu e-uric acid akheka ngenxa ye-uric acid eningi egazini, akheke ezicutshini ezixhumene, futhi abangele ubuhlungu, ukuvuvukala, ububomvu, nokuvuvukala. Ukuze uqede i-gout, ufuna ukwehlisa ukukhiqizwa kwe-uric acid.

Kunezizathu ezimbalwa ezingabangela ukukhiqizwa kwe-uric acid:

amaprotheni kanye ne-gout

Odokotela bavame ukusikisela ukudla okunamaprotheni aphansi, okunenyama encane ye-gout.

Ukucabanga ukuthi imithombo eminingi yamaprotheni iqukethe izinhlanganisela ezibizwa ngokuthi ama-purines angazandulela ku-uric acid.

Ama-Purines akha izakhi zofuzo ku-DNA ne-RNA, futhi lapho ugaya ama-purines, umzimba wakho uwahlephula abe uric acid. Imithombo ecebile kakhulu yama-purines inyama, inhlanzi kanye nezitho zomzimba.

Ithiyori iwukuthi ukwehlisa umthamo wakho we-purine kuzokwehlisa amazinga akho e-uric acid futhi, ngokulandelayo, kunciphise ingozi ye-gout.

Kodwa-ke, isayensi yokusetshenziswa kwamaprotheni kanye ne-gout ixubile.

Isibonelo, ucwaningo oluthile lwahlobanisa ukusetshenziswa kwenyama nokudla kwasolwandle nengozi eyengeziwe ye-gout ( ² ). Kodwa ocwaningweni olulawulwa kakhulu, abacwaningi bathola ukuthi izinyanga eziyisithupha zokudla okunamaprotheni amaningi, ukudla okuphansi kwe-carb empeleni kwehlisa amazinga e-uric acid kuma-74 abahlanganyeli abakhuluphele noma abakhuluphele.

Ababhali baphetha ngokuthi "ukudla kwe-Atkins (ukudla okunamaprotheni amaningi ngaphandle kokuvinjelwa kwekhalori) kunganciphisa [i-serum uric acid] amazinga naphezu kokulayisha okukhulu kwe-purine."

Eminye idatha ibonisa ukuthi imifino yezilwane inamazinga e-uric acid aphezulu kunalabo abadla inyama, okuphakamisa ukuthi kuningi okusengozini kunokudla amaprotheni kuphela.

Ucwaningo lwakamuva luthole ukuthi uma udla ukudla okunamaprotheni amaningi, izinso zakho azinankinga yokukhipha i-uric acid eziyenzayo kuma-purines.

Ngamanye amazwi, ama-purines amaningi angena, akhipha i-uric acid eyengeziwe ( ³ ). Uma nje izinso zakho zisasebenza kahle, amaprotheni abonakala engawandisi amathuba okuba ne-gout.

ubisi kanye ne-gout

Ngenxa yokuthi imikhiqizo yobisi inamaprotheni amaningi (kanye nama-purines), abanye bakhathazeka ngokuthi ukudla ubisi, ushizi, noma iyogathi kuzokwandisa ingozi ye-gout.

Kodwa ocwaningweni olukhulu olwalandela abantu abangu-47.150 iminyaka engu-12, abacwaningi bathola okuphambene: Ukusetshenziswa kobisi kwakuhlobene ngokuphambene nengozi ye-gout. Nakuba lolu cwaningo lungafakazeli imbangela nomphumela, kubonakala sengathi imikhiqizo yobisi icacile uma kukhulunywa nge-gout.

ushukela bese uphonsa

Ushukela uyingozi kakhulu ku-gout kunamaprotheni. Ikakhulukazi, i-fructose, ushukela ojwayelekile esithelweni nesiraphu yommbila.

I-Fructose ikhulisa ukukhiqizwa kwe-uric acid, kuyilapho ngesikhathi esifanayo ivimbela ukucaciswa kwe-uric acid.

Isibindi sakho sicubungula i-fructose ngokuhlukile kunezinye ushukela. Uma isibindi sakho sigcwele i-fructose, singaphazamisa ukugaya kwamaprotheni futhi siqede i-ATP (amandla amaselula).

Lapho i-ATP yakho yehla, ukukhiqizwa kwe-uric acid yakho kuyanda ( ⁴ ) - futhi njengoba uke wafunda ngaphambili, i-uric acid ephezulu iyisici esiyingozi kakhulu se-gout.

Isizathu sesibili sokugwema i-fructose sihilela ukukhishwa kwe-uric acid. Uma udla i-fructose eningi ngokuhamba kwesikhathi, wehlisa ikhono lezinso zakho lokukhipha i-uric acid.

Kodwa akukona nje ukusetshenziswa okungapheli, ngisho nomthamo owodwa we-fructose wehlisa ukucaciswa komchamo ( ⁵ ).

Umthombo ovame kakhulu we-fructose ekudleni kwesimanje isiraphu yommbila ephezulu ye-fructose. Uzoyithola kukho konke kusukela eziphuzweni ezithambile kuya kumakhukhi kuya kokusanhlamvu. Yenza iphuzu ukugwema isiraphu yommbila ephezulu ye-fructose; uzozizwa ungcono kakhulu ngaphandle kwayo.

i-insulin kanye ne-gout

Ushukela, i-fructose noma okunye, nakho kwandisa ingozi ye-gout ngokulawula amazinga e-insulin.

Uma udla ushukela omningi, izinga likashukela egazini liyakhuphuka. Ukuphendula, amanyikwe wakho akhipha i-insulin, yakho Isilawuli Soshukela wegazi, ukugoqa ushukela oweqile egazini futhi uwuyise kumaseli akho, lapho ungaguqulwa ube amandla (ukuze usetshenziswe ngokushesha) noma amafutha (ukugcina amandla).

Kodwa uma udla ushukela omningi njalo, ushukela wegazi lakho uhlala uphakeme njalo, futhi i-insulin iyayeka ukuxhumana namangqamuzana akho ngokuphumelelayo.

Lesi simo Esaziwa ngokuthi ukumelana ne-insulin (noma i-metabolic syndrome), lesi simo sibangela ukuthi amanyikwe akhiphe i-insulin eyengeziwe ukuze enze umsebenzi ofanayo.

Amazinga aphezulu we-insulin ejikelezayo anciphisa ukucaciswa kwe-uric acid ( ⁶ ). Ukuze ugweme i-gout, udinga ukuhlala uzwela ku-insulin. Indlela engcono kakhulu yokwenza lokhu ukususa ushukela ekudleni kwakho.

utshwala kanye ne-gout

Utshwala buyinto esungulwe kahle engozini yokuthola isifo sohudo, futhi kwandisa amathuba okuba uhlaselwe yi-gout uma usunaso.

Ocwaningweni olubhekiwe, abacwaningi balandele amadoda angama-47.150 angenawo umlando we-gout iminyaka engu-12. Bathole ukuthi ukuphuza ubhiya, kanye nezinga elincane lemimoya, kwakuhlotshaniswa kakhulu nobungozi be-gout. Ngokumangalisayo, iwayini lalingekho ( ⁷ ).

Elinye iqembu labacwaningi labuza umbuzo ohlukile: Kulabo kakade abaphethwe i-gout, ukuphuza utshwala kwandisa kangakanani ingozi yokuhlaselwa yi-gout?

Bathola ukuthi zonke izinhlobo zotshwala, kuhlanganisa newayini, zazixhunyaniswe nengozi eyengeziwe yokuqhuma kwegout phakathi namahora angu-24 ukuphuza.

Indlela yokugwema i-gout

Ukugwema i-gout kwehla ekunciphiseni izimbangela buyisa ye-uric acid ephakeme ebalwe esigabeni sangaphambilini. Inyama, amafutha, namaprotheni akubonakali kunomthelela omkhulu ku-gout.

Esikhundleni salokho, yehlisa i-fructose notshwala ukuze ugcine amazinga e-uric acid enempilo futhi unciphise ingozi ye-gout. Kukhona i-fructose esithelweni, kodwa umthombo oyinhloko we-fructose isiraphu yommbila ephezulu ye-fructose. Uma ufuna ukwenza into eyodwa ukunciphisa ingozi ye-gout, susa isiraphu yommbila ene-fructose ekudleni kwakho.

Esinye isici esiyingozi se-gout, i-metabolic syndrome, nayo ihlotshaniswa nokusetshenziswa ushukela. Uma une-metabolic syndrome noma uhlobo 2 sikashukela, ushukela ophezulu wegazi, i-insulin ephezulu, ukukhuluphala ngokweqile, nomfutho wegazi ophakeme, usengozini enkulu ye-gout.

Ukulungisa i-metabolic syndrome kanye nokumelana ne-insulin ngeke kwenzeke ngokuphazima kweso. Kodwa ukudla okune-carb ephansi (njengokudla kwe-ketogenic) kuye kwaboniswa ukugcina ukudla ushukela egazini, bathuthukisa ukuzwela kwe-insulin futhi bakhuthaze ukuncipha kwesisindo.

Ukudla kwe-ketogenic kuyindlela enhle yokuvimbela i-gout.

Uzofuna futhi ukuhlala u-hydrated ukuze uvimbele i-gout. Qiniseka ukuthi uphuza amanzi anele. Uma uphelelwa amanzi emzimbeni, umzimba wakho uyayeka ukukhipha i-uric acid, okusho ukuthi amakristalu e-uric acid maningi amathuba okuthi akheke emalungeni akho.

Okokugcina, idlanzana lemithi, iningi layo okuyizidakamizwa ezibangela ukuphelelwa amanzi emzimbeni, liye laxhunyaniswa nengozi eyengeziwe ye-gout. Futhi abacwaningi bathole ukuthi i-aspirin yedosi ephansi ingaphazamisa ukusebenza kwezinso futhi ithinte ukucaciswa kwe-uric acid.

Okufanele ukwenze uma une-gout

Into yokuqala okufanele uyenze uma une-gout ukubonana nodokotela. Angase akunikeze imithi ebizwa ngokuthi i-xanthine oxidase inhibitors ukuze ehlise amazinga akho e-uric acid.

Ngaphezu kwalokho, uzodinga ukucabanga ngokushintsha kwendlela yokuphila, ikakhulukazi uma kuziwa ekudleni nasekuzivocavoceni.

Ongakudla uma une-gout

Ukudla okuthile kanye nezithako zokudla kukhonjisiwe ukuvikela ngokumelene ne-gout futhi kungase kunciphise izimpawu ze-gout. Lokhu kubandakanya:

• I-Vitamin C: Ibangela ukuthi izinso zikhiphe i-uric acid eyengeziwe.⁸ ).
• Amafutha e-Olive.
• Imikhiqizo yobisi.
• Ama-Cherries - aboniswe ukunciphisa i-plasma uric acid kwabesifazane ( ⁹ ).
• Amanzi amaminerali: avimbela ukwakheka kwamakristalu e-uric acid.¹⁰ ).
• Ikhofi: Ukusetshenziswa kwekhofi ngokusesilinganisweni kunciphisa amazinga e-uric acid.¹¹ ).

ukuzivocavoca kanye ne-gout

Ngaphezu kokulungiswa kokudla okungenhla, uhlelo lokuzivocavoca njalo lungasiza nge-gout.

Ukuzivocavoca:

• Yandisa ukuzwela kwe-insulin futhi ingathuthukisa i-metabolic syndrome.¹² ).
• Iqeda i-glycogen yesibindi, equkethe i-uric acid-ekhuthaza i-fructose.
• Ivimbela i-hyperinsulinemia, engasiza ekususweni kwe-uric acid ( ¹³ ).

Kuthiwani ngokudla kwe-ketogenic kwe-gout?

Ingabe ukudla kwe-ketogenic kwandisa ingozi yakho ye-gout?

Phakathi namasonto amabili okuqala okudla kwe-ketogenic, ungase ubone ukwanda kwesikhashana engozini yakho ye-gout. Lokhu kungenxa yokuthi amazinga aphezulu e-ketone avimbela izinso zakho ekuhlanzeni kahle i-uric acid. [ ¹⁴ ).

Kodwa nazi izindaba ezinhle: Ngemva kwamasonto amabili kuya kwamathathu, ujwayela i-keto, futhi amazinga akho e-uric acid abuyela kwesijwayelekile. Empeleni, ekudleni kwe-ketogenic, ingozi yesikhathi eside ye-gout (ikalwa ngamazinga e-uric acid) empeleni iyancipha ( ¹⁵ ).

Okokuqala, i-keto igcina amazinga akho e-insulin esezingeni. Uma ukhawulela ama-carbs ekudleni okunamafutha aphezulu e-ketogenic, ushukela wegazi lakho uhlala uphansi, futhi lapho ushukela wakho wegazi uhlala uphansi, i-insulin yakho ihlala iphansi, futhi. I-insulin ephansi, uma ukhumbula, isiza izinso zakho ukukhipha i-uric acid.

Kukhona nezinye izindlela ezidlalwayo. Ekudleni kwe-ketogenic, isibindi sakho sikhiqiza ama-ketone, ne-beta-hydroxybutyrate (BHB) ebaluleke kakhulu.

Muva nje, iqembu labacwaningi base-Yale lithole ukuthi i-bhB yehlisa ingozi yokuqubuka kwe-gout kumagundane. I-BHB inciphisa ukuvuvukala ngokuvimbela ingxenye yamasosha omzimba ebizwa ngokuthi i-NLRP3 inflammasome, enganciphisa ingozi yokuhlaselwa yi-gout.

I-Keto kanye ne-gout: okubalulekile

Izinto eziningi zandisa ingozi yokuthuthukisa i-gout. Ukuphelelwa amanzi emzimbeni, i-fructose, ukumelana ne-insulin, notshwala kwandisa i-uric acid, eqhuba ukwakheka kwekristalu futhi ekugcineni i-gout.

Ukuze uvimbele i-gout, gwema lezi zici eziyingozi futhi uzame ukulungisa ukudla njengokuphuza ikhofi nokuthatha uvithamini C. Futhi cabangela uhlelo lokuzivocavoca oluvamile ukuze wandise ukuzwela kwakho ku-insulin.

Okokugcina, uma kuziwa engozini ye-gout, ungakhathazeki ngokudla amafutha namaprotheni. Ushukela (ikakhulukazi i-fructose) i-macro ukugwema Ukudla okune-carb ephansi ye-ketogenic kubonakala kuyisu elihle lesikhathi eside lokunciphisa ingozi ye-gout. Ukuze ufunde kabanzi mayelana nokuya ku-keto, hlola yethu I-Basic Keto Guide Kulula ukulandela.